SLIT vs. Allergy Shots: Which Immunotherapy Is Right for You?
If you're tired of sneezing, sniffling, and relying on allergy meds just to get through the day, immunotherapy might be your ticket to long-term relief. But should you choose sublingual immunotherapy (SLIT)—the needle-free allergy drops—or stick with traditional allergy shots (SCIT)?
Let’s break down how they compare—and which one might be your best bet for beating allergies for good.
What Is Sublingual Immunotherapy (SLIT)?
SLIT is a modern, needle-free way to treat allergies by placing a small dose of allergens under your tongue in the form of a tablet or liquid. Over time, your immune system gets used to these allergens, helping to reduce allergic reactions. Unlike traditional allergy shots, which require regular visits to the doctor's office, SLIT is something you can take at home.
How SLIT Works
- Customized Drops/Tablets: Made for your specific allergies (pollen, dust mites, etc.)
- Daily Dosing: Just a few drops under the tongue at home—no doctor visits needed after the first dose
- Long-Term Relief: Takes 3–6 months to start working, with best results after 3–5 years
"While allergy management strategies can minimize reactions and control symptoms, sublingual immunotherapy (SLIT) aims to build lasting resistance, potentially reducing or eliminating the need for those other methods." - Dr. Radabaugh.
Who Can Benefit from SLIT?
✔ Busy adults who can’t make weekly doctor visits
✔ Kids (FDA-approved for ages 5+) who fear needles
✔ People with mild to moderate allergies (especially pollen, dust mites, pet dander)
A 2025 meta-analysis found SLIT reduces allergy symptoms by 40–60%—similar to shots—but with fewer side effects.
Allergy Shots (SCIT): The Classic Approach
Allergy shots, or Subcutaneous Immunotherapy (SCIT), have been around for over 100 years. This treatment involves getting regular injections of allergens under the skin, typically in your arm. The goal is to gradually desensitize your immune system to these allergens over time.
How Shots Work
- Build-Up Phase: Weekly injections for 3–6 months
- Maintenance Phase: Monthly shots for 3–5 years
- Strong Results: Effective for severe allergies (including insect venom and mold)
Who Can Benefit from SCIT?
✔ Patients with multiple or severe allergies
✔ Those who don’t mind needles
✔ People who want insurance-covered treatment (shots are more likely to be covered)
SLIT vs. Shots: Key Differences
| Feature | SLIT (Sublingual Immunotherapy) | Allergy Shots (SCIT) |
|---|---|---|
| Method of Treatment | Small dose of allergens placed under the tongue | Allergens injected under the skin |
| Frequency | Daily (usually at home) | Weekly to Monthly |
| Pain/Discomfort | None (no needles) | Mild sting at injection site |
| Convenience | Very convenient, can be done at home | Requires frequent trips to the doctor's office |
| Customization | Can mix multiple allergens | Highly customizable |
| Effectiveness | Highly effective for a wide range of allergens | Proven effective, especially for seasonal allergies |
| Side Effects | Mild irritation, itching, or swelling under the tongue | Redness, swelling, or allergic reaction at the injection site |
Is SLIT Available in Jacksonville?
Yes, it is! If you're in Jacksonville, you can now access Sublingual Immunotherapy (SLIT) treatment at Jacksonville Sinus & Nasal Institute. This means you don’t have to travel far to take advantage of this modern, effective allergy treatment. Our experienced team of specialists will evaluate your condition and help you determine if SLIT is the right choice for you.
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